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Tumor necrosis factor receptor type 1-associated DEATH domain protein is a protein in humans that is encoded by TRADD gene. The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12
The following TRADD reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TRADD Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA024145GA01HU | TRADD Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA621879ESR2HU | TRADD Antibody |
Human | ELISA, WB, IHC |
| CSB-PA004322 | TRADD Antibody |
Human,Mouse,Monkey | WB, IHC, ELISA |
| CSB-PA621879EA01HU | TRADD Antibody |
Human, Rat | ELISA, WB, IHC, IF, IP |
| CSB-PA621879EB01HU | TRADD Antibody, HRP conjugated |
Human | ELISA |
| CSB-PA621879EC01HU | TRADD Antibody, FITC conjugated |
Human | |
| CSB-PA621879ED01HU | TRADD Antibody, Biotin conjugated |
Human | ELISA |
TRADD Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA867432XA01DIL | tradd Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
TRADD Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP621879HU CSB-BP621879HU CSB-MP621879HU CSB-EP621879HU-B |
Recombinant Human Tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP621879HU | Recombinant Human Tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD) |
E.coli |
TRADD Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP633137OEI CSB-EP633137OEI CSB-BP633137OEI CSB-MP633137OEI CSB-EP633137OEI-B |
Recombinant Oncorhynchus mykiss Tumor necrosis factor receptor type 1-associated DEATH domain protein (tradd) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRADD Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP642522BO CSB-EP642522BO CSB-BP642522BO CSB-MP642522BO CSB-EP642522BO-B |
Recombinant Bovine Tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRADD Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP658365XBE CSB-EP658365XBE CSB-BP658365XBE CSB-MP658365XBE CSB-EP658365XBE-B |
Recombinant Xenopus laevis Tumor necrosis factor receptor type 1-associated DEATH domain protein (tradd) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRADD Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP659708MO CSB-EP659708MO CSB-BP659708MO CSB-MP659708MO CSB-EP659708MO-B |
Recombinant Mouse Tumor necrosis factor receptor type 1-associated DEATH domain protein (Tradd) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRADD Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP867432DIL CSB-EP867432DIL CSB-BP867432DIL CSB-MP867432DIL CSB-EP867432DIL-B |
Recombinant Danio rerio Tumor necrosis factor receptor type 1-associated DEATH domain protein (tradd) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Tumor necrosis factor receptor type 1-associated DEATH domain protein is a protein in humans that is encoded by the TRADD gene [1]. TRADD is a death domain-containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-κB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis.TRADD can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1 and is involved in the Fas-induced cell death pathway. The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12.
[1] Hsu H, Xiong J, Goeddel DV (June 1995). The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation [J]. Cell. 81 (4): 495–504.
